2ig2: Difference between revisions

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[[Image:2ig2.~~gif~~|left|200px]]

[[Image:2ig2.png|left|200px]]

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~~'''~~DIR PRIMAERSTRUKTUR DES KRISTALLISIERBAREN MONOKLONALEN IMMUNOGLOBULINS IGG1 KOL. II. AMINOSAEURESEQUENZ DER L-KETTE, LAMBDA-TYP, SUBGRUPPE I (GERMAN)~~'''~~

===DIR PRIMAERSTRUKTUR DES KRISTALLISIERBAREN MONOKLONALEN IMMUNOGLOBULINS IGG1 KOL. II. AMINOSAEURESEQUENZ DER L-KETTE, LAMBDA-TYP, SUBGRUPPE I (GERMAN)===

~~==Overview==~~

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~~The immunoglobulin Kol was the first intact antibody molecule which was characterized by high~~-~~resolution X~~-ray crystallography. Furthermore the complete amino-acid sequence of the heavy (H)-chain is known. Here we report the complete amino-acid sequence of the light (L)-chain of the monoclonal immunoglobulin Kol (IgG1). The ~~polypeptide has an Mr of 22~~,~~781~~, ~~consists of 216 amino acids and due~~ to ~~its structure is of~~ the ~~lambda-type~~. ~~With the characteristic amino acids threonine, asparagine, threonine, glycine and lysine in positions 101, 114, 116, 154, and 165~~, ~~respectively the Kol L-chain~~ is of the ~~Mcg isotype~~. ~~With the proteins Mcg, Mot, Bur, Loc and Mem six myeloma~~-~~derived amino~~-~~acid sequences of the same isotype are known. The amino-acid sequence of the N-terminal variable part is characteristic of subgroup 1. This contribution completes the primary structure of IgG1 Kol.~~

The line below this paragraph, {{ABSTRACT_PUBMED_2713105}}, adds the Publication Abstract to the page

(as it appears on PubMed at http://www.pubmed.gov), where 2713105 is the PubMed ID number.

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==About this Structure==

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[[Category: Marquart, M.]]

[[Category: Immunoglobulin]]

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Sun May 4 07~~:27:46 2008''

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 08:20:02 2008''

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-[[Image:2ig2.gif|left|200px]]
+{{Seed}}
+[[Image:2ig2.png|left|200px]]
 <!--
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 {{STRUCTURE_2ig2|  PDB=2ig2  |  SCENE=  }}
-'''DIR PRIMAERSTRUKTUR DES KRISTALLISIERBAREN MONOKLONALEN IMMUNOGLOBULINS IGG1 KOL. II. AMINOSAEURESEQUENZ DER L-KETTE, LAMBDA-TYP, SUBGRUPPE I (GERMAN)'''
+===DIR PRIMAERSTRUKTUR DES KRISTALLISIERBAREN MONOKLONALEN IMMUNOGLOBULINS IGG1 KOL. II. AMINOSAEURESEQUENZ DER L-KETTE, LAMBDA-TYP, SUBGRUPPE I (GERMAN)===
-==Overview==
+<!--
-The immunoglobulin Kol was the first intact antibody molecule which was characterized by high-resolution X-ray crystallography. Furthermore the complete amino-acid sequence of the heavy (H)-chain is known. Here we report the complete amino-acid sequence of the light (L)-chain of the monoclonal immunoglobulin Kol (IgG1). The polypeptide has an Mr of 22,781, consists of 216 amino acids and due to its structure is of the lambda-type. With the characteristic amino acids threonine, asparagine, threonine, glycine and lysine in positions 101, 114, 116, 154, and 165, respectively the Kol L-chain is of the Mcg isotype. With the proteins Mcg, Mot, Bur, Loc and Mem six myeloma-derived amino-acid sequences of the same isotype are known. The amino-acid sequence of the N-terminal variable part is characteristic of subgroup 1. This contribution completes the primary structure of IgG1 Kol.
+The line below this paragraph, {{ABSTRACT_PUBMED_2713105}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 2713105 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_2713105}}
 ==About this Structure==
@@ Line 25: / Line 29: @@
 [[Category: Marquart, M.]]
 [[Category: Immunoglobulin]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May  4 07:27:46 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 08:20:02 2008''