2ntr: Difference between revisions

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-[[Image:2ntr.jpg|left|200px]]
+{{Seed}}
+[[Image:2ntr.png|left|200px]]
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 {{STRUCTURE_2ntr|  PDB=2ntr  |  SCENE=  }}
-'''Crystal structure of Human Bace-1 bound to inhibitor'''
+===Crystal structure of Human Bace-1 bound to inhibitor===
-==Overview==
+<!--
-BACE-1 is a flexible enzyme with experimentally determined motion in the flap region, the catalytic aspartates, and the 10s loop. Four in-house crystallographically determined complexes of tertiary carbinamine inhibitors revealed 10s loop motion in the S(3) pocket. These X-ray structures were used to correlate K(i) values, which span over five orders of magnitude, with the calculated interaction energy, using the Merck Molecular Force Field for a series of 19 tertiary carbinamine inhibitors.
+The line below this paragraph, {{ABSTRACT_PUBMED_17112725}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 17112725 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_17112725}}
 ==About this Structure==
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 [[Category: Bace]]
 [[Category: Hydrolase]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May  4 09:54:05 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 09:16:02 2008''

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