2byh: Difference between revisions

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-[[Image:2byh.gif|left|200px]]
+{{Seed}}
+[[Image:2byh.png|left|200px]]
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 {{STRUCTURE_2byh|  PDB=2byh  |  SCENE=  }}
-'''3-(5-CHLORO-2,4-DIHYDROXYPHENYL)-PYRAZOLE-4-CARBOXAMIDES AS INHIBITORS OF THE HSP90 MOLECULAR CHAPERONE'''
+===3-(5-CHLORO-2,4-DIHYDROXYPHENYL)-PYRAZOLE-4-CARBOXAMIDES AS INHIBITORS OF THE HSP90 MOLECULAR CHAPERONE===
-==Overview==
+<!--
-Information from X-ray crystal structures of Hsp90 inhibitors bound to the human Hsp90 molecular chaperone was used to assist in the design of 3-(5-chloro-2,4-dihydroxyphenyl)-pyrazole-4-carboxamides as novel inhibitors of Hsp90. Accessing an extra interaction with the protein via Phe138 gave a significant increase in binding potency compared to similar analogues that do not make this interaction.
+The line below this paragraph, {{ABSTRACT_PUBMED_16213716}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 16213716 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_16213716}}
 ==About this Structure==
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 [[Category: Phosphorylation]]
 [[Category: Pyrazole]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May  3 20:58:23 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 14:09:45 2008''

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