205d: Difference between revisions

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[[Image:205d.jpg|left|200px]]
{{Seed}}
[[Image:205d.png|left|200px]]


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{{STRUCTURE_205d|  PDB=205d  |  SCENE=  }}  
{{STRUCTURE_205d|  PDB=205d  |  SCENE=  }}  


'''STRUCTURE OF AN RNA DOUBLE HELIX INCLUDING URACIL-URACIL BASE PAIRS IN AN INTERNAL LOOP'''
===STRUCTURE OF AN RNA DOUBLE HELIX INCLUDING URACIL-URACIL BASE PAIRS IN AN INTERNAL LOOP===




==Overview==
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The crystal structure of the RNA dodecamer 5'-GGACUUUGGUCC-3' has been determined from X-ray diffraction data to 2.6 A resolution. This oligomer forms an asymmetric double helix in the crystal. Four consecutive non-Watson-Crick base-pairs are formed in the middle of the duplex including the first intrahelical U-U (or T-T) pairs observed in an oligonucleotide crystal structure. Two different conformations of U-U pairs are observed in the context of the surrounding sequence. One of these pairs is highly twisted, allowing a bound water to bridge across strands in the major groove. The crystal packing illustrates a new form of RNA helix-helix interaction.
The line below this paragraph, {{ABSTRACT_PUBMED_7719854}}, adds the Publication Abstract to the page
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{{ABSTRACT_PUBMED_7719854}}


==About this Structure==
==About this Structure==
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[[Category: Internal loop]]
[[Category: Internal loop]]
[[Category: Mismatched]]
[[Category: Mismatched]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May  3 18:17:54 2008''
 
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