1oko: Difference between revisions

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{{Seed}}
[[Image:1oko.gif|left|200px]]
[[Image:1oko.gif|left|200px]]


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{{STRUCTURE_1oko|  PDB=1oko  |  SCENE=  }}  
{{STRUCTURE_1oko|  PDB=1oko  |  SCENE=  }}  


'''CRYSTAL STRUCTURE OF PSEUDOMONAS AERUGINOSA LECTIN 1 COMPLEXED WITH GALACTOSE AT 1.6 A RESOLUTION'''
===CRYSTAL STRUCTURE OF PSEUDOMONAS AERUGINOSA LECTIN 1 COMPLEXED WITH GALACTOSE AT 1.6 A RESOLUTION===




==Overview==
<!--
The structure of the tetrameric Pseudomonas aeruginosa lectin I (PA-IL) in complex with galactose and calcium was determined at 1.6 A resolution, and the native protein was solved at 2.4 A resolution. Each monomer adopts a beta-sandwich fold with ligand binding site at the apex. All galactose hydroxyl groups, except O1, are involved in a hydrogen bond network with the protein and O3 and O4 also participate in the co-ordination of the calcium ion. The stereochemistry of calcium galactose binding is reminiscent of that observed in some animal C-type lectins. The structure of the complex provides a framework for future design of anti-bacterial compounds.
The line below this paragraph, {{ABSTRACT_PUBMED_14644431}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 14644431 is the PubMed ID number.
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{{ABSTRACT_PUBMED_14644431}}


==About this Structure==
==About this Structure==
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[[Category: Galactose binding]]
[[Category: Galactose binding]]
[[Category: Lectin]]
[[Category: Lectin]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May  3 03:58:30 2008''
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 18:30:26 2008''
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