2ong: Difference between revisions

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[[Image:2ong.gif|left|200px]]
{{Seed}}
[[Image:2ong.png|left|200px]]


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{{STRUCTURE_2ong|  PDB=2ong  |  SCENE=  }}  
{{STRUCTURE_2ong|  PDB=2ong  |  SCENE=  }}  


'''Crystal Structure of of limonene synthase with 2-fluorogeranyl diphosphate (FGPP).'''
===Crystal Structure of of limonene synthase with 2-fluorogeranyl diphosphate (FGPP).===




==Overview==
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The crystal structure of (4S)-limonene synthase from Mentha spic ata, a metal ion-dependent monoterpene cyclase that catalyzes the coupled isomerization and cyclization of geranyl diphosphate, is reported at 2.7-A; resolution in two forms liganded to the substrate and intermediate analogs, 2-fluorogeranyl diphosphate and 2-fluorolinalyl diphosphate, respectively. The implications of these findings are described for domain interactions in the homodimer and for changes in diphosphate-metal ion coordination and substrate binding conformation in the course of the multistep reaction.
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{{ABSTRACT_PUBMED_17372193}}


==About this Structure==
==About this Structure==
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[[Category: Monoterpene cyclase]]
[[Category: Monoterpene cyclase]]
[[Category: Monoterpene synthase]]
[[Category: Monoterpene synthase]]
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