1urn: Difference between revisions

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[[Image:1urn.jpg|left|200px]]
{{Seed}}
[[Image:1urn.png|left|200px]]


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{{STRUCTURE_1urn|  PDB=1urn  |  SCENE=  }}  
{{STRUCTURE_1urn|  PDB=1urn  |  SCENE=  }}  


'''U1A MUTANT/RNA COMPLEX + GLYCEROL'''
===U1A MUTANT/RNA COMPLEX + GLYCEROL===




==Overview==
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The crystal structure of the RNA-binding domain of the small nuclear ribonucleoprotein U1A bound to a 21-nucleotide RNA hairpin has been determined at 1.92 A resolution. The ten-nucleotide RNA loop binds to the surface of the beta-sheet as an open structure, and the AUUGCAC sequence of the loop interacts extensively with the conserved RNP1 and RNP2 motifs and the C-terminal extension of the RNP domain. These interactions include stacking of RNA bases with aromatic side chains of proteins and many direct and water-mediated hydrogen bonds. The structure reveals the stereochemical basis for sequence-specific RNA recognition by the RNP domain.
The line below this paragraph, {{ABSTRACT_PUBMED_7984237}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 7984237 is the PubMed ID number.
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{{ABSTRACT_PUBMED_7984237}}


==About this Structure==
==About this Structure==
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[[Category: Protein-rna complex]]
[[Category: Protein-rna complex]]
[[Category: Single strand]]
[[Category: Single strand]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May  3 11:35:44 2008''
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 19:11:08 2008''
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