3bgp: Difference between revisions

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-[[Image:3bgp.gif|left|200px]]
+{{Seed}}
+[[Image:3bgp.png|left|200px]]
 <!--
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 {{STRUCTURE_3bgp|  PDB=3bgp  |  SCENE=  }}
-'''Human Pim-1 complexed with a benzoisoxazole inhibitor VX1'''
+===Human Pim-1 complexed with a benzoisoxazole inhibitor VX1===
-==Overview==
+<!--
-To supplement the hits from a high throughput screen, docking was performed against Pim-1 kinase. Glide docking was augmented with a filter to require traditional or aromatic CH..O hydrogen bonds to the kinase hinge. Four diverse actives, of 96 molecules assayed, had K(i) values between 0.091 and 4.5 microM. This gives a 14-fold enrichment over the earlier HTS run, and the two crystal structures solved confirmed the binding modes predicted by docking.
+The line below this paragraph, {{ABSTRACT_PUBMED_18290603}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 18290603 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_18290603}}
 ==About this Structure==
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 [[Category: Serine/threonine-protein kinase]]
 [[Category: Transferase]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Apr 30 13:38:41 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 20:32:11 2008''

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