2phr: Difference between revisions

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[[Image:2phr.jpg|left|200px]]
{{Seed}}
[[Image:2phr.png|left|200px]]


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{{STRUCTURE_2phr|  PDB=2phr  |  SCENE=  }}  
{{STRUCTURE_2phr|  PDB=2phr  |  SCENE=  }}  


'''Pterocarpus angolensis lectin (PAL) in complex with Man-7D1'''
===Pterocarpus angolensis lectin (PAL) in complex with Man-7D1===




==Overview==
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The crystal structure of Pterocarpus angolensis seed lectin is presented in complex with a series of high mannose (Man) oligosaccharides ranging from Man-5 to Man-9. Despite that several of the nine Man residues of Man-9 have the potential to bind in the monosaccharide-binding site, all oligomannoses are bound in the same unique way, employing the tetrasaccharide sequence Manalpha(1-2)Manalpha(1-6)[Manalpha(1-3)]Manalpha(1-. Isothermal titration calorimetry titration experiments using Man-5, Man-9, and the Man-9-containing glycoprotein soybean (Glycine max) agglutinin as ligands confirm the monovalence of Man-9 and show a 4-times higher affinity for Man-9 when it is presented to P. angolensis seed lectin in a glycoprotein context.
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(as it appears on PubMed at http://www.pubmed.gov), where 17556509 is the PubMed ID number.
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{{ABSTRACT_PUBMED_17556509}}


==About this Structure==
==About this Structure==
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[[Category: High mannose]]
[[Category: High mannose]]
[[Category: Lectin]]
[[Category: Lectin]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May  4 13:08:14 2008''
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 20:48:53 2008''

Revision as of 17:48, 28 July 2008

File:2phr.png

Template:STRUCTURE 2phr

Pterocarpus angolensis lectin (PAL) in complex with Man-7D1

Template:ABSTRACT PUBMED 17556509

About this Structure

2PHR is a Single protein structure of sequence from Pterocarpus angolensis. Full crystallographic information is available from OCA.

Reference

How a plant lectin recognizes high mannose oligosaccharides., Garcia-Pino A, Buts L, Wyns L, Imberty A, Loris R, Plant Physiol. 2007 Aug;144(4):1733-41. Epub 2007 Jun 7. PMID:17556509

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