2hek: Difference between revisions

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[[Image:2hek.gif|left|200px]]
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{{STRUCTURE_2hek|  PDB=2hek  |  SCENE=  }}  
{{STRUCTURE_2hek|  PDB=2hek  |  SCENE=  }}  


'''Crystal structure of O67745, a hypothetical protein from Aquifex aeolicus at 2.0 A resolution.'''
===Crystal structure of O67745, a hypothetical protein from Aquifex aeolicus at 2.0 A resolution.===




==Overview==
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Using single-wavelength anomalous dispersion data obtained from a gold-derivatized crystal, the X-ray crystal structure of the protein 067745_AQUAE from the prokaryotic organism Aquifex aeolicus has been determined to a resolution of 2.0 A. Amino-acid residues 1-371 of the 44 kDa protein were identified by Pfam as an HD domain and a member of the metal-dependent phosphohydrolase superfamily (accession No. PF01966). Although three families from this large and diverse group of enzymatic proteins are represented in the PDB, the structure of 067745_AQUAE reveals a unique fold that is unlike the others and that is likely to represent a new subfamily, further organizing the families and characterizing the proteins. Data are presented that provide the first insights into the structural organization of the proteins within this clan and a distal alternative GDP-binding domain outside the metal-binding active site is proposed.
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{{ABSTRACT_PUBMED_17565173}}


==About this Structure==
==About this Structure==
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[[Category: Structural genomic]]
[[Category: Structural genomic]]
[[Category: Unknown function]]
[[Category: Unknown function]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May  4 06:11:41 2008''
 
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Revision as of 19:24, 28 July 2008

File:2hek.png

Template:STRUCTURE 2hek

Crystal structure of O67745, a hypothetical protein from Aquifex aeolicus at 2.0 A resolution.

Template:ABSTRACT PUBMED 17565173

About this Structure

2HEK is a Single protein structure of sequence from Aquifex aeolicus. Full crystallographic information is available from OCA.

Reference

Structure of O67745_AQUAE, a hypothetical protein from Aquifex aeolicus., Oganesyan V, Adams PD, Jancarik J, Kim R, Kim SH, Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 May 1;63(Pt, 5):369-74. Epub 2007 Apr 28. PMID:17565173

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