1ntn: Difference between revisions

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[[Image:1ntn.gif|left|200px]]
{{Seed}}
[[Image:1ntn.png|left|200px]]


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{{STRUCTURE_1ntn|  PDB=1ntn  |  SCENE=  }}  
{{STRUCTURE_1ntn|  PDB=1ntn  |  SCENE=  }}  


'''THE CRYSTAL STRUCTURE OF NEUROTOXIN-I FROM NAJA NAJA OXIANA AT 1.9 ANGSTROMS RESOLUTION'''
===THE CRYSTAL STRUCTURE OF NEUROTOXIN-I FROM NAJA NAJA OXIANA AT 1.9 ANGSTROMS RESOLUTION===




==Overview==
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Neurotoxin-1 from Naja naja oxiana venom (NTX-1) has been crystallized by vapor diffusion in sitting drops. The crystals have cell dimensions of a = 25.2 A, b = 75.6 A, c = 35.9 A, and are in space group P2(1)2(1)2(1). Three-dimensional data to 1.9 A have been recorded by a Syntex P2(1) automatic diffractometer. The atomic structure of the toxin has been determined by molecular replacement using the alpha-cobratoxin (alpha-CTX) as the search model. The position of 534 non-hydrogen protein atoms have been determined. The model contains 65 water molecules. Refinement has led to an R-factor of 19.3% at 1.9 A resolution. The secondary and tertiary structures of NTX-1 have been analyzed and a comparison with structure of the alpha-CTX has been made.
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{{ABSTRACT_PUBMED_8458425}}


==About this Structure==
==About this Structure==
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[[Category: Wilson, K.]]
[[Category: Wilson, K.]]
[[Category: Postsynaptic neurotoxin]]
[[Category: Postsynaptic neurotoxin]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May  3 02:57:53 2008''
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 23:22:36 2008''

Revision as of 20:22, 28 July 2008

File:1ntn.png

Template:STRUCTURE 1ntn

THE CRYSTAL STRUCTURE OF NEUROTOXIN-I FROM NAJA NAJA OXIANA AT 1.9 ANGSTROMS RESOLUTION

Template:ABSTRACT PUBMED 8458425

About this Structure

1NTN is a Single protein structure of sequence from Naja oxiana. Full crystallographic information is available from OCA.

Reference

Three-dimensional structure of neurotoxin-1 from Naja naja oxiana venom at 1.9 A resolution., Nickitenko AV, Michailov AM, Betzel C, Wilson KS, FEBS Lett. 1993 Apr 5;320(2):111-7. PMID:8458425

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