2i0j: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older editNewer edit →
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,613 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,613 edits
No edit summary
Line 1: Line 1:
[[Image:2i0j.gif|left|200px]]
{{Seed}}
[[Image:2i0j.png|left|200px]]


<!--
<!--
Line 9: Line 10:
{{STRUCTURE_2i0j|  PDB=2i0j  |  SCENE=  }}  
{{STRUCTURE_2i0j|  PDB=2i0j  |  SCENE=  }}  


'''Benzopyrans are Selective Estrogen Receptor beta Agonists (SERBAs) with Novel Activity in Models of Benign Prostatic Hyperplasia'''
===Benzopyrans are Selective Estrogen Receptor beta Agonists (SERBAs) with Novel Activity in Models of Benign Prostatic Hyperplasia===




==Overview==
<!--  
Benzopyran selective estrogen receptor beta agonist-1 (SERBA-1) shows potent, selective binding and agonist function in estrogen receptor beta (ERbeta) in vitro assays. X-ray crystal structures of SERBA-1 in ERalpha and beta help explain observed beta-selectivity of this ligand. SERBA-1 in vivo demonstrates involution of the ventral prostate in CD-1 mice (ERbeta effect), while having no effect on gonadal hormone levels (ERalpha effect) at 10x the efficacious dose, consistent with in vitro properties of this molecule.
The line below this paragraph, {{ABSTRACT_PUBMED_17034120}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 17034120 is the PubMed ID number.
-->
{{ABSTRACT_PUBMED_17034120}}


==About this Structure==
==About this Structure==
Line 24: Line 28:
[[Category: Wang, Y.]]
[[Category: Wang, Y.]]
[[Category: Nuclear receptor ligand binding domain]]
[[Category: Nuclear receptor ligand binding domain]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May  4 06:55:54 2008''
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 00:33:05 2008''
Retrieved from "https://proteopedia.org/2i0j"