1xe3: Difference between revisions

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[[Image:1xe3.jpg|left|200px]]
{{Seed}}
[[Image:1xe3.png|left|200px]]


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{{STRUCTURE_1xe3|  PDB=1xe3  |  SCENE=  }}  
{{STRUCTURE_1xe3|  PDB=1xe3  |  SCENE=  }}  


'''Crystal Structure of purine nucleoside phosphorylase DeoD from Bacillus anthracis'''
===Crystal Structure of purine nucleoside phosphorylase DeoD from Bacillus anthracis===




==Overview==
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Protein structures from the causative agent of anthrax (Bacillus anthracis) are being determined as part of a structural genomics programme. Amongst initial candidates for crystallographic analysis are enzymes involved in nucleotide biosynthesis, since these are recognized as potential targets in antibacterial therapy. Purine nucleoside phosphorylase is a key enzyme in the purine-salvage pathway. The crystal structure of purine nucleoside phosphorylase (DeoD) from B. anthracis has been solved by molecular replacement at 2.24 A resolution and refined to an R factor of 18.4%. This is the first report of a DeoD structure from a Gram-positive bacterium.
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{{ABSTRACT_PUBMED_16511068}}


==About this Structure==
==About this Structure==
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[[Category: Structural genomic]]
[[Category: Structural genomic]]
[[Category: Structural proteomics in europe]]
[[Category: Structural proteomics in europe]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Apr 13 08:14:13 2008''
 
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