2gtn: Difference between revisions

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-[[Image:2gtn.gif|left|200px]]
+{{Seed}}
+[[Image:2gtn.png|left|200px]]
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 {{STRUCTURE_2gtn|  PDB=2gtn  |  SCENE=  }}
-'''Mutated MAP kinase P38 (Mus Musculus) in complex with Inhbitor PG-951717'''
+===Mutated MAP kinase P38 (Mus Musculus) in complex with Inhbitor PG-951717===
-==Overview==
+<!--
-A series of C-2, C-8, and N-9 trisubstituted purine based inhibitors of TNF-alpha production are described. The most potent analogs showed low nanomolar activity against LPS-induced TNF-alpha production in a THP-1 cell based assay. The SAR of the series was optimized with the aid of X-ray co-crystal structures of these inhibitors bound with mutated p38 (mp38).
+The line below this paragraph, {{ABSTRACT_PUBMED_16750367}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 16750367 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_16750367}}
 ==About this Structure==
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 [[Category: Map kinase p38]]
 [[Category: P38]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May  4 05:31:18 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 03:45:51 2008''

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