2bre: Difference between revisions

From Proteopedia
Jump to navigationJump to search
OCA (talk | contribs)
No edit summary
OCA (talk | contribs)
No edit summary
Line 1: Line 1:
[[Image:2bre.gif|left|200px]]
{{Seed}}
[[Image:2bre.png|left|200px]]


<!--
<!--
Line 9: Line 10:
{{STRUCTURE_2bre|  PDB=2bre  |  SCENE=  }}  
{{STRUCTURE_2bre|  PDB=2bre  |  SCENE=  }}  


'''STRUCTURE OF A HSP90 INHIBITOR BOUND TO THE N-TERMINUS OF YEAST HSP90.'''
===STRUCTURE OF A HSP90 INHIBITOR BOUND TO THE N-TERMINUS OF YEAST HSP90.===




==Overview==
<!--
High-throughput screening identified the 3,4-diarylpyrazole CCT018159 as a novel and potent (7.1 microM) inhibitor of Hsp90 ATPase activity. Here, we describe the synthesis of CCT018159 and a number of close analogues together with data on their biochemical properties. Some initial structure-activity relationships are discussed, as well as the crystal structure of CCT018159 bound to Hsp90.
The line below this paragraph, {{ABSTRACT_PUBMED_15955698}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 15955698 is the PubMed ID number.
-->
{{ABSTRACT_PUBMED_15955698}}


==About this Structure==
==About this Structure==
Line 31: Line 35:
[[Category: Inhibitor]]
[[Category: Inhibitor]]
[[Category: Multigene family]]
[[Category: Multigene family]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May  3 20:41:26 2008''
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 04:46:31 2008''