1sus: Difference between revisions

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[[Image:1sus.~~gif~~|left|200px]]

[[Image:1sus.png|left|200px]]

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~~'''~~Crystal structure of alfalfa feruoyl coenzyme A 3-O-methyltransferase~~'''~~

===Crystal structure of alfalfa feruoyl coenzyme A 3-O-methyltransferase===

~~==Overview==~~

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~~Caffeoyl coenzyme A 3~~-O-~~methyltransferases (CCoAOMTs) are S-adenosyl-l-methionine-dependent O-methyltransferases (OMTs) involved in lignin biosynthesis. Plant CCoAOMTs belong to a distinct family of OMTs~~, ~~more closely related~~ to the ~~mammalian catechol OMTs than to other plant OMTs~~. ~~The crystal structure of alfalfa (Medicago sativa~~) ~~CCoAOMT in complex with~~ the ~~reaction products S-adenosine-l-homocysteine and feruloyl/sinapoyl CoAs presented here belong to a structurally and mechanistically distinct family of plant small molecule OMTs~~. ~~These structures provide a new understanding of the substrate preferences and the catalytic mechanism accompanying CCoAOMT~~-~~mediated O~~-~~methylation of CoA-linked phenylpropanoid substrates.~~

The line below this paragraph, {{ABSTRACT_PUBMED_15734921}}, adds the Publication Abstract to the page

(as it appears on PubMed at http://www.pubmed.gov), where 15734921 is the PubMed ID number.

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==About this Structure==

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[[Category: Protein-cofactor-substrate complex]]

[[Category: Rossmann fold]]

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Sat May 3 09~~:09:26 2008''

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 05:30:01 2008''

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-[[Image:1sus.gif|left|200px]]
+{{Seed}}
+[[Image:1sus.png|left|200px]]
 <!--
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 {{STRUCTURE_1sus|  PDB=1sus  |  SCENE=  }}
-'''Crystal structure of alfalfa feruoyl coenzyme A 3-O-methyltransferase'''
+===Crystal structure of alfalfa feruoyl coenzyme A 3-O-methyltransferase===
-==Overview==
+<!--
-Caffeoyl coenzyme A 3-O-methyltransferases (CCoAOMTs) are S-adenosyl-l-methionine-dependent O-methyltransferases (OMTs) involved in lignin biosynthesis. Plant CCoAOMTs belong to a distinct family of OMTs, more closely related to the mammalian catechol OMTs than to other plant OMTs. The crystal structure of alfalfa (Medicago sativa) CCoAOMT in complex with the reaction products S-adenosine-l-homocysteine and feruloyl/sinapoyl CoAs presented here belong to a structurally and mechanistically distinct family of plant small molecule OMTs. These structures provide a new understanding of the substrate preferences and the catalytic mechanism accompanying CCoAOMT-mediated O-methylation of CoA-linked phenylpropanoid substrates.
+The line below this paragraph, {{ABSTRACT_PUBMED_15734921}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 15734921 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_15734921}}
 ==About this Structure==
@@ Line 30: / Line 34: @@
 [[Category: Protein-cofactor-substrate complex]]
 [[Category: Rossmann fold]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May  3 09:09:26 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 05:30:01 2008''