2ffh: Difference between revisions

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[[Image:2ffh.gif|left|200px]]
{{Seed}}
[[Image:2ffh.png|left|200px]]


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{{STRUCTURE_2ffh|  PDB=2ffh  |  SCENE=  }}  
{{STRUCTURE_2ffh|  PDB=2ffh  |  SCENE=  }}  


'''THE SIGNAL SEQUENCE BINDING PROTEIN FFH FROM THERMUS AQUATICUS'''
===THE SIGNAL SEQUENCE BINDING PROTEIN FFH FROM THERMUS AQUATICUS===




==Overview==
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The crystal structure of the signal sequence binding subunit of the signal recognition particle (SRP) from Thermus aquaticus reveals a deep groove bounded by a flexible loop and lined with side chains of conserved hydrophobic residues. The groove defines a flexible, hydrophobic environment that is likely to contribute to the structural plasticity necessary for SRP to bind signal sequences of different lengths and amino acid sequence. The structure also reveals a helix-turn-helix motif containing an arginine-rich alpha helix that is required for binding to SRP RNA and is implicated in forming the core of an extended RNA binding surface.
The line below this paragraph, {{ABSTRACT_PUBMED_9695947}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 9695947 is the PubMed ID number.
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{{ABSTRACT_PUBMED_9695947}}


==About this Structure==
==About this Structure==
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[[Category: Signal sequence-binding]]
[[Category: Signal sequence-binding]]
[[Category: Srp54]]
[[Category: Srp54]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May  4 03:49:56 2008''
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 07:29:03 2008''
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