1p9n: Difference between revisions

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[[Image:1p9n.jpg|left|200px]]
{{Seed}}
[[Image:1p9n.png|left|200px]]


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{{STRUCTURE_1p9n|  PDB=1p9n  |  SCENE=  }}  
{{STRUCTURE_1p9n|  PDB=1p9n  |  SCENE=  }}  


'''Crystal structure of Escherichia coli MobB.'''
===Crystal structure of Escherichia coli MobB.===




==Overview==
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The crystal structure of Escherichia coli MobB, an enzyme involved in the final step of molybdenum-cofactor biosynthesis, forms intertwined dimers. Each molecule consists of two segments and requires the second monomer for stable folding. Dimerization buries a quarter of the solvent-accessible area of the monomer. These dimers assemble into a hexagonal lattice with P6(4)22 symmetry and occupy only approximately 25% of the unit-cell volume. The symmetry-related dimers associate tightly into a helical structure with a diameter of 250 A and a pitch of 98 A. Two such helices are intertwined, shifted by 49 A along the sixfold axis. Within the crystal, these helices form thin-walled cylinders with an external diameter of 250 A and an internal diameter of 190 A. Their center is filled with solvent. These cylinders pack closely together, forming a hexagonal lattice with the highest possible packing density. This arrangement of dimers allows extensive intermolecular contacts with 75% solvent content in the crystal.
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{{ABSTRACT_PUBMED_14646116}}


==About this Structure==
==About this Structure==
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[[Category: Montreal-kingston bacterial structural genomics initiative]]
[[Category: Montreal-kingston bacterial structural genomics initiative]]
[[Category: Structural genomic]]
[[Category: Structural genomic]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May  3 04:51:20 2008''
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 08:22:51 2008''

Revision as of 05:22, 29 July 2008

File:1p9n.png

Template:STRUCTURE 1p9n

Crystal structure of Escherichia coli MobB.

Template:ABSTRACT PUBMED 14646116

About this Structure

1P9N is a Single protein structure of sequence from Escherichia coli. Full crystallographic information is available from OCA.

Reference

Molecules of Escherichia coli MobB assemble into densely packed hollow cylinders in a crystal lattice with 75% solvent content., Rangarajan SE, Tocilj A, Li Y, Iannuzzi P, Matte A, Cygler M, Acta Crystallogr D Biol Crystallogr. 2003 Dec;59(Pt 12):2348-52. Epub 2003, Nov 27. PMID:14646116

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