1nq3: Difference between revisions

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[[Image:1nq3.gif|left|200px]]
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{{STRUCTURE_1nq3|  PDB=1nq3  |  SCENE=  }}  
{{STRUCTURE_1nq3|  PDB=1nq3  |  SCENE=  }}  


'''Crystal structure of the mammalian tumor associated antigen UK114'''
===Crystal structure of the mammalian tumor associated antigen UK114===




==Overview==
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The tumour-associated antigen UK114, isolated from goat liver, belongs to the YER057c/YIL051c/YjgF protein family, which has members in both the prokaryotes and eukaryotes. The crystal structure of a mammalian representative, goat UK114, was determined, revealing a trimeric arrangement in the crystal. It was confirmed by ultracentrifugation that UK114 is a trimer in solution. These results are in agreement with the published structures of homologues from unicellular organisms, but contrast with those reported for the rat homologue of UK114, for which a dimeric quaternary structure was proposed.
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{{ABSTRACT_PUBMED_12925811}}


==About this Structure==
==About this Structure==
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[[Category: Uk114]]
[[Category: Uk114]]
[[Category: Yer057c/yil051c/yjgf protein family]]
[[Category: Yer057c/yil051c/yjgf protein family]]
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Revision as of 05:58, 29 July 2008

File:1nq3.png

Template:STRUCTURE 1nq3

Crystal structure of the mammalian tumor associated antigen UK114

Template:ABSTRACT PUBMED 12925811

About this Structure

1NQ3 is a Single protein structure of sequence from Capra hircus. Full crystallographic information is available from OCA.

Reference

Structure and oligomeric state of the mammalian tumour-associated antigen UK114., Deriu D, Briand C, Mistiniene E, Naktinis V, Grutter MG, Acta Crystallogr D Biol Crystallogr. 2003 Sep;59(Pt 9):1676-8. Epub 2003, Aug 19. PMID:12925811

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