1rxp: Difference between revisions

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[[Image:1rxp.gif|left|200px]]
{{Seed}}
[[Image:1rxp.png|left|200px]]


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{{STRUCTURE_1rxp|  PDB=1rxp  |  SCENE=  }}  
{{STRUCTURE_1rxp|  PDB=1rxp  |  SCENE=  }}  


'''STRUCTURE OF TRYPSIN (ORTHORHOMBIC) WITH 1-(4-TERT-BUTYLCARBAMOYL- PIPERAZINE-1-CARBONYL)-3-(3-GUANIDINO-PROPYL)-4-OXO-AZETIDINE-2-CARBOXYLIC ACID'''
===STRUCTURE OF TRYPSIN (ORTHORHOMBIC) WITH 1-(4-TERT-BUTYLCARBAMOYL- PIPERAZINE-1-CARBONYL)-3-(3-GUANIDINO-PROPYL)-4-OXO-AZETIDINE-2-CARBOXYLIC ACID===




==Overview==
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A series of nonguanidine N1-activated C4-carboxy azetidinone tryptase inhibitors was prepared by solid-phase methodology to quickly assess the SAR associated with distal functionality on the N1-activating group. From these studies, potent inhibitors with improved specificity were discovered.
The line below this paragraph, {{ABSTRACT_PUBMED_15081015}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 15081015 is the PubMed ID number.
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{{ABSTRACT_PUBMED_15081015}}


==About this Structure==
==About this Structure==
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[[Category: Serine protease]]
[[Category: Serine protease]]
[[Category: Tryptase inhibitor]]
[[Category: Tryptase inhibitor]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May  3 08:02:00 2008''
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 09:33:40 2008''