2b52: Difference between revisions

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[[Image:2b52.gif|left|200px]]
{{Seed}}
[[Image:2b52.png|left|200px]]


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{{STRUCTURE_2b52|  PDB=2b52  |  SCENE=  }}  
{{STRUCTURE_2b52|  PDB=2b52  |  SCENE=  }}  


'''Human cyclin dependent kinase 2 (CDK2) complexed with DPH-042562'''
===Human cyclin dependent kinase 2 (CDK2) complexed with DPH-042562===




==Overview==
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New indeno[1,2-c]pyrazol-4-one cyclin dependent kinase inhibitors have been disclosed. The most promising compounds are nanomolar enzyme inhibitors with excellent activity against tumor cells. The most advanced compound retains cell culture activity even in the presence of human serum proteins. The most advanced compound did not kill the normal fibroblast line AG1523.
The line below this paragraph, {{ABSTRACT_PUBMED_14698155}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 14698155 is the PubMed ID number.
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{{ABSTRACT_PUBMED_14698155}}


==About this Structure==
==About this Structure==
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[[Category: Phosphorylation]]
[[Category: Phosphorylation]]
[[Category: Protein kinase]]
[[Category: Protein kinase]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May  3 19:51:56 2008''
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 09:48:41 2008''