2cw2: Difference between revisions

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[[Image:2cw2.~~gif~~|left|200px]]

[[Image:2cw2.png|left|200px]]

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~~'''~~Crystal structure of Superoxide dismutase from P. Marinus~~'''~~

===Crystal structure of Superoxide dismutase from P. Marinus===

~~==Overview==~~

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~~Perkinsus marinus~~, ~~a facultative intracellular parasite of~~ the eastern oyster Crassostrea virginica, is responsible for mass mortalities of oyster populations. P. marinus trophozoites survive and proliferate within oyster hemocytes, invading most tissues and fluids, thus causing a systemic infection that eventually kills the ~~host~~. ~~The phagocytosis of P~~. ~~marinus trophozoites lacks a respiratory burst~~, ~~suggesting that the parasite has mechanisms that actively abrogate the host's oxidative defense responses. One mechanism and the first line of defense against oxidative damage~~ is the ~~dismutation of superoxide radical to molecular oxygen and hydrogen peroxide by superoxide dismutases (SODs)~~. ~~P. marinus possesses two iron~~-~~cofactored SODs, PmSOD1 and PmSOD2. Here, the crystallization and X~~-~~ray structures of both PmSOD1 and PmSOD2 are presented.~~

The line below this paragraph, {{ABSTRACT_PUBMED_17077482}}, adds the Publication Abstract to the page

(as it appears on PubMed at http://www.pubmed.gov), where 17077482 is the PubMed ID number.

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==About this Structure==

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[[Category: Vasta, G R.]]

[[Category: Sod]]

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Sat May 3 23~~:11:09 2008''

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 10:27:03 2008''

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-[[Image:2cw2.gif|left|200px]]
+{{Seed}}
+[[Image:2cw2.png|left|200px]]
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 {{STRUCTURE_2cw2|  PDB=2cw2  |  SCENE=  }}
-'''Crystal structure of Superoxide dismutase from P. Marinus'''
+===Crystal structure of Superoxide dismutase from P. Marinus===
-==Overview==
+<!--
-Perkinsus marinus, a facultative intracellular parasite of the eastern oyster Crassostrea virginica, is responsible for mass mortalities of oyster populations. P. marinus trophozoites survive and proliferate within oyster hemocytes, invading most tissues and fluids, thus causing a systemic infection that eventually kills the host. The phagocytosis of P. marinus trophozoites lacks a respiratory burst, suggesting that the parasite has mechanisms that actively abrogate the host's oxidative defense responses. One mechanism and the first line of defense against oxidative damage is the dismutation of superoxide radical to molecular oxygen and hydrogen peroxide by superoxide dismutases (SODs). P. marinus possesses two iron-cofactored SODs, PmSOD1 and PmSOD2. Here, the crystallization and X-ray structures of both PmSOD1 and PmSOD2 are presented.
+The line below this paragraph, {{ABSTRACT_PUBMED_17077482}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 17077482 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_17077482}}
 ==About this Structure==
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 [[Category: Vasta, G R.]]
 [[Category: Sod]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May  3 23:11:09 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 10:27:03 2008''