1thf: Difference between revisions

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[[Image:1thf.jpg|left|200px]]
{{Seed}}
[[Image:1thf.png|left|200px]]


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{{STRUCTURE_1thf|  PDB=1thf  |  SCENE=  }}  
{{STRUCTURE_1thf|  PDB=1thf  |  SCENE=  }}  


'''CYCLASE SUBUNIT OF IMIDAZOLEGLYCEROLPHOSPHATE SYNTHASE FROM THERMOTOGA MARITIMA'''
===CYCLASE SUBUNIT OF IMIDAZOLEGLYCEROLPHOSPHATE SYNTHASE FROM THERMOTOGA MARITIMA===




==Overview==
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The atomic structures of two proteins in the histidine biosynthesis pathway consist of beta/alpha barrels with a twofold repeat pattern. It is likely that these proteins evolved by twofold gene duplication and gene fusion from a common half-barrel ancestor. These ancestral domains are not visible as independent domains in the extant proteins but can be inferred from a combination of sequence and structural analysis. The detection of subdomain structures may be useful in efforts to search genome sequences for functionally and structurally related proteins.
The line below this paragraph, {{ABSTRACT_PUBMED_10968789}}, adds the Publication Abstract to the page
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{{ABSTRACT_PUBMED_10968789}}


==About this Structure==
==About this Structure==
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[[Category: Thermophile]]
[[Category: Thermophile]]
[[Category: Tim-barrel]]
[[Category: Tim-barrel]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May  3 09:57:09 2008''
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 12:01:46 2008''