2p8h: Difference between revisions

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[[Image:2p8h.jpg|left|200px]]
{{Seed}}
[[Image:2p8h.png|left|200px]]


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{{STRUCTURE_2p8h|  PDB=2p8h  |  SCENE=  }}  
{{STRUCTURE_2p8h|  PDB=2p8h  |  SCENE=  }}  


'''Crystal structure of human beta secretase complexed with inhibitor'''
===Crystal structure of human beta secretase complexed with inhibitor===




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==Reference==
==Reference==
Design and Synthesis of 2,3,5-Substituted Imidazolidin-4-one Inhibitors of BACE-1., Barrow JC, Rittle KE, Ngo PL, Selnick HG, Graham SL, Pitzenberger SM, McGaughey GB, Colussi D, Lai MT, Huang Q, Tugusheva K, Espeseth AS, Simon AJ, Munshi SK, Vacca JP, ChemMedChem. 2007 Jul 9;2(7):995-999. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17458843 17458843]
Design and synthesis of 2,3,5-substituted imidazolidin-4-one inhibitors of BACE-1., Barrow JC, Rittle KE, Ngo PL, Selnick HG, Graham SL, Pitzenberger SM, McGaughey GB, Colussi D, Lai MT, Huang Q, Tugusheva K, Espeseth AS, Simon AJ, Munshi SK, Vacca JP, ChemMedChem. 2007 Jul;2(7):995-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17458843 17458843]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Memapsin 2]]
[[Category: Memapsin 2]]
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[[Category: Bace]]
[[Category: Bace]]
[[Category: Hydrolase]]
[[Category: Hydrolase]]
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Revision as of 10:10, 29 July 2008

File:2p8h.png

Template:STRUCTURE 2p8h

Crystal structure of human beta secretase complexed with inhibitor

About this Structure

2P8H is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Design and synthesis of 2,3,5-substituted imidazolidin-4-one inhibitors of BACE-1., Barrow JC, Rittle KE, Ngo PL, Selnick HG, Graham SL, Pitzenberger SM, McGaughey GB, Colussi D, Lai MT, Huang Q, Tugusheva K, Espeseth AS, Simon AJ, Munshi SK, Vacca JP, ChemMedChem. 2007 Jul;2(7):995-9. PMID:17458843

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