2c5b: Difference between revisions

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[[Image:2c5b.jpg|left|200px]]
{{Seed}}
[[Image:2c5b.png|left|200px]]


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{{STRUCTURE_2c5b|  PDB=2c5b  |  SCENE=  }}  
{{STRUCTURE_2c5b|  PDB=2c5b  |  SCENE=  }}  


'''X-RAY CRYSTAL STRUCTURE OF 5'-FLUORODEOXYADENOSINE SYNTHASE FROM STREPTOMYCES CATTLEYA COMPLEXED WITH 2'DEOXY-5'DEOXY-FLUOROADENOSINE.'''
===X-RAY CRYSTAL STRUCTURE OF 5'-FLUORODEOXYADENOSINE SYNTHASE FROM STREPTOMYCES CATTLEYA COMPLEXED WITH 2'DEOXY-5'DEOXY-FLUOROADENOSINE.===




==Overview==
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The fluorinase enzyme from Streptomyces cattleya displays an unusual ability in biocatalysis in that it forms a C-F bond. We now report that the enzyme will accept 2'-deoxyadenosine in place of adenosine substrates, and structural evidence reveals a reorganisation in hydrogen bonding to accommodate this substrate series. It emerges from this study that the enzyme does not require a planar ribose conformation of the substrate to catalyse C-F bond formation.
The line below this paragraph, {{ABSTRACT_PUBMED_16604208}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 16604208 is the PubMed ID number.
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{{ABSTRACT_PUBMED_16604208}}


==About this Structure==
==About this Structure==
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[[Category: Streptomyces cattleya]]
[[Category: Streptomyces cattleya]]
[[Category: Transferase]]
[[Category: Transferase]]
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