1pho: Difference between revisions

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[[Image:1pho.gif|left|200px]]
{{Seed}}
[[Image:1pho.png|left|200px]]


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{{STRUCTURE_1pho|  PDB=1pho  |  SCENE=  }}  
{{STRUCTURE_1pho|  PDB=1pho  |  SCENE=  }}  


'''CRYSTAL STRUCTURES EXPLAIN FUNCTIONAL PROPERTIES OF TWO E. COLI PORINS'''
===CRYSTAL STRUCTURES EXPLAIN FUNCTIONAL PROPERTIES OF TWO E. COLI PORINS===




==Overview==
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Porins form aqueous channels that aid the diffusion of small hydrophilic molecules across the outer membrane of Gram-negative bacteria. The crystal structures of matrix porin and phosphoporin both reveal trimers of identical subunits, each subunit consisting of a 16-stranded anti-parallel beta-barrel containing a pore. A long loop inside the barrel contributes to a constriction of the channel where the charge distribution affects ion selectivity. The structures explain at the molecular level functional characteristics and their alterations by known mutations.
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{{ABSTRACT_PUBMED_1380671}}


==About this Structure==
==About this Structure==
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[[Category: Schirmer, T.]]
[[Category: Schirmer, T.]]
[[Category: Outer membrane protein]]
[[Category: Outer membrane protein]]
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