2arx: Difference between revisions

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[[Image:2arx.gif|left|200px]]
{{Seed}}
[[Image:2arx.png|left|200px]]


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{{STRUCTURE_2arx|  PDB=2arx  |  SCENE=  }}  
{{STRUCTURE_2arx|  PDB=2arx  |  SCENE=  }}  


'''Pterocarpus angolensis seed lectin in complex with the decasaccharide NA2F'''
===Pterocarpus angolensis seed lectin in complex with the decasaccharide NA2F===




==Overview==
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The crystal structure of Pterocarpus angolensis lectin is determined in its ligand-free state, in complex with the fucosylated biantennary complex type decasaccharide NA2F, and in complex with a series of smaller oligosaccharide constituents of NA2F. These results together with thermodynamic binding data indicate that the complete oligosaccharide binding site of the lectin consists of five subsites allowing the specific recognition of the pentasaccharide GlcNAc beta(1-2)Man alpha(1-3)[GlcNAc beta(1-2)Man alpha(1-6)]Man. The mannose on the 1-6 arm occupies the monosaccharide binding site while the GlcNAc residue on this arm occupies a subsite that is almost identical to that of concanavalin A (con A). The core mannose and the GlcNAc beta(1-2)Man moiety on the 1-3 arm on the other hand occupy a series of subsites distinct from those of con A.
The line below this paragraph, {{ABSTRACT_PUBMED_16704415}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 16704415 is the PubMed ID number.
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{{ABSTRACT_PUBMED_16704415}}


==About this Structure==
==About this Structure==
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[[Category: Lectin]]
[[Category: Lectin]]
[[Category: Legume lectin]]
[[Category: Legume lectin]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May  3 19:24:16 2008''
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 15:24:10 2008''

Revision as of 12:24, 29 July 2008

File:2arx.png

Template:STRUCTURE 2arx

Pterocarpus angolensis seed lectin in complex with the decasaccharide NA2F

Template:ABSTRACT PUBMED 16704415

About this Structure

2ARX is a Single protein structure of sequence from Pterocarpus angolensis. Full crystallographic information is available from OCA.

Reference

Structural basis for the recognition of complex-type biantennary oligosaccharides by Pterocarpus angolensis lectin., Buts L, Garcia-Pino A, Imberty A, Amiot N, Boons GJ, Beeckmans S, Versees W, Wyns L, Loris R, FEBS J. 2006 Jun;273(11):2407-20. PMID:16704415

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