3e63: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

[[Image:3e63.jpg|left|200px]]

The ~~entry~~ 3e63 ~~is ON HOLD~~ ~~until Paper Publication~~

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~~Authors: Antonysamy, S.S.~~

===Fragment based discovery of JAK-2 inhibitors===

~~Description: Fragment based discovery of JAK-2 inhibitors~~

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct ~~8 09~~:18:25 2008''

==Disease==

Known disease associated with this structure: Leukemia, acute myelogenous OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147796 147796]], Myelofibrosis, idiopathic OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147796 147796]], Myeloproliferative disorder with erythrocytosis OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147796 147796]], Polycythemia vera OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147796 147796]], Thrombocythemia, essential OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147796 147796]], Budd-Chiari syndrome OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147796 147796]]

==About this Structure==

3E63 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3E63 OCA].

[[Category: Homo sapiens]]

[[Category: Non-specific protein-tyrosine kinase]]

[[Category: Single protein]]

[[Category: Antonysamy, S S.]]

[[Category: Atp-binding]]

[[Category: Chromosomal rearrangement]]

[[Category: Disease mutation]]

[[Category: Drug discovery]]

[[Category: Fragment based]]

[[Category: Jak2]]

[[Category: Kinase]]

[[Category: Membrane]]

[[Category: Nucleotide-binding]]

[[Category: Phosphoprotein]]

[[Category: Polymorphism]]

[[Category: Proto-oncogene]]

[[Category: Sh2 domain]]

[[Category: Transferase]]

[[Category: Tyrosine-protein kinase]]

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 15 15:27:43 2008''

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+{{Seed}}
+[[Image:3e63.jpg|left|200px]]
-The entry 3e63 is ON HOLD  until Paper Publication
+<!--
+The line below this paragraph, containing "STRUCTURE_3e63", creates the "Structure Box" on the page.
+You may change the PDB parameter (which sets the PDB file loaded into the applet)
+or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+or leave the SCENE parameter empty for the default display.
+-->
+{{STRUCTURE_3e63|  PDB=3e63  |  SCENE=  }}
-Authors: Antonysamy, S.S.
+===Fragment based discovery of JAK-2 inhibitors===
-Description: Fragment based discovery of JAK-2 inhibitors
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct  8 09:18:25 2008''
+==Disease==
+Known disease associated with this structure: Leukemia, acute myelogenous OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147796 147796]], Myelofibrosis, idiopathic OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147796 147796]], Myeloproliferative disorder with erythrocytosis OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147796 147796]], Polycythemia vera OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147796 147796]], Thrombocythemia, essential OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147796 147796]], Budd-Chiari syndrome OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147796 147796]]
+==About this Structure==
+E63 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3E63 OCA].
+[[Category: Homo sapiens]]
+[[Category: Non-specific protein-tyrosine kinase]]
+[[Category: Single protein]]
+[[Category: Antonysamy, S S.]]
+[[Category: Atp-binding]]
+[[Category: Chromosomal rearrangement]]
+[[Category: Disease mutation]]
+[[Category: Drug discovery]]
+[[Category: Fragment based]]
+[[Category: Jak2]]
+[[Category: Kinase]]
+[[Category: Membrane]]
+[[Category: Nucleotide-binding]]
+[[Category: Phosphoprotein]]
+[[Category: Polymorphism]]
+[[Category: Proto-oncogene]]
+[[Category: Sh2 domain]]
+[[Category: Transferase]]
+[[Category: Tyrosine-protein kinase]]
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 15 15:27:43 2008''