3f66: Difference between revisions
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[[Image:3f66.jpg|left|200px]] | |||
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{{STRUCTURE_3f66| PDB=3f66 | SCENE= }} | |||
===Human c-Met Kinase in complex with quinoxaline inhibitor=== | |||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec | <!-- | ||
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(as it appears on PubMed at http://www.pubmed.gov), where 19059779 is the PubMed ID number. | |||
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{{ABSTRACT_PUBMED_19059779}} | |||
==Disease== | |||
Known disease associated with this structure: Hepatocellular carcinoma, childhood type OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=164860 164860]], Renal cell carcinoma, papillary, familial and sporadic OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=164860 164860]], Autism, suseptibility to, 9 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=164860 164860]] | |||
==About this Structure== | |||
3F66 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3F66 OCA]. | |||
==Reference== | |||
Discovery of a novel series of quinoxalines as inhibitors of c-Met kinase., Porter J, Lumb S, Lecomte F, Reuberson J, Foley A, Calmiano M, le Riche K, Edwards H, Delgado J, Franklin RJ, Gascon-Simorte JM, Maloney A, Meier C, Batchelor M, Bioorg Med Chem Lett. 2008 Nov 21. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/19059779 19059779] | |||
[[Category: Homo sapiens]] | |||
[[Category: Receptor protein-tyrosine kinase]] | |||
[[Category: Ceska, T.]] | |||
[[Category: Meier, C.]] | |||
[[Category: Alternative splicing]] | |||
[[Category: Atp-binding]] | |||
[[Category: C-met]] | |||
[[Category: Chromosomal rearrangement]] | |||
[[Category: Disease mutation]] | |||
[[Category: Glycoprotein]] | |||
[[Category: Kinase]] | |||
[[Category: Membrane]] | |||
[[Category: Nucleotide-binding]] | |||
[[Category: Phosphoprotein]] | |||
[[Category: Polymorphism]] | |||
[[Category: Protein kinase]] | |||
[[Category: Proto-oncogene]] | |||
[[Category: Quinoxaline]] | |||
[[Category: Receptor]] | |||
[[Category: Repeat]] | |||
[[Category: Signal]] | |||
[[Category: Transferase]] | |||
[[Category: Transmembrane]] | |||
[[Category: Tyrosine-protein kinase.]] | |||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 24 11:36:15 2008'' | |||
