3d06: Difference between revisions

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'''Unreleased structure'''
{{Seed}}
[[Image:3d06.jpg|left|200px]]


The entry 3d06 is ON HOLD until Paper Publication
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{{STRUCTURE_3d06|  PDB=3d06  |  SCENE=  }}


Authors: Suad, O., Rozenberg, H., Diskin-Posner, Y., Kessler, N., Shimon, L.J.W., Frolow, F., Brosh, R., Liran, A., Rotter, V., Shakked, Z.
===Human p53 core domain with hot spot mutation R249S (I)===


Description: p53 (1)


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{{ABSTRACT_PUBMED_18996393}}
 
==Disease==
Known disease associated with this structure: Adrenal cortical carcinoma OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=191170 191170]], Breast cancer OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=191170 191170]], Colorectal cancer OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=191170 191170]], Hepatocellular carcinoma OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=191170 191170]], Histiocytoma OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=191170 191170]], Li-Fraumeni syndrome OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=191170 191170]], Multiple malignancy syndrome OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=191170 191170]], Nasopharyngeal carcinoma OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=191170 191170]], Osteosarcoma OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=191170 191170]], Pancreatic cancer OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=191170 191170]], Thyroid carcinoma OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=191170 191170]]
 
==About this Structure==
3D06 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D06 OCA].
 
==Reference==
<ref group="xtra">PMID:18996393</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Frolow, F.]]
[[Category: Rozenberg, H.]]
[[Category: Shakked, Z.]]
[[Category: Shimon, L J.W.]]
[[Category: Suad, O.]]
[[Category: Acetylation]]
[[Category: Activator]]
[[Category: Alternative splicing]]
[[Category: Anti-oncogene]]
[[Category: Apoptosis]]
[[Category: Cell cycle]]
[[Category: Covalent protein-rna linkage]]
[[Category: Cytoplasm]]
[[Category: Disease mutation]]
[[Category: Dna-binding]]
[[Category: Endoplasmic reticulum]]
[[Category: Glycoprotein]]
[[Category: Host-virus interaction]]
[[Category: Li-fraumeni syndrome]]
[[Category: Loop-sheet-helix motif]]
[[Category: Metal-binding]]
[[Category: Methylation]]
[[Category: Mutant protein]]
[[Category: Nucleus]]
[[Category: P53]]
[[Category: Phosphoprotein]]
[[Category: Polymorphism]]
[[Category: Transcription]]
[[Category: Transcription regulation]]
[[Category: Ubl conjugation]]
[[Category: Zinc]]
 
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