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==About this Structure==
==About this Structure==
2CHM is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CHM OCA].  
2CHM is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CHM OCA].  


==Reference==
==Reference==
A novel series of potent and selective PDE5 inhibitors with potential for high and dose-independent oral bioavailability., Allerton CM, Barber CG, Beaumont KC, Brown DG, Cole SM, Ellis D, Lane CA, Maw GN, Mount NM, Rawson DJ, Robinson CM, Street SD, Summerhill NW, J Med Chem. 2006 Jun 15;49(12):3581-94. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16759100 16759100]
<ref group="xtra">PMID:16759100</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Allerton, C M.N.]]
[[Category: Allerton, C M.N.]]
[[Category: Barber, C G.]]
[[Category: Barber, C G.]]
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[[Category: Zinc]]
[[Category: Zinc]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 12:21:54 2008''
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Revision as of 08:00, 16 February 2009

File:2chm.png

Template:STRUCTURE 2chm

CRYSTAL STRUCTURE OF N2 SUBSTITUTED PYRAZOLO PYRIMIDINONES-A FLIPPED BINDING MODE IN PDE5

Template:ABSTRACT PUBMED 16759100

About this Structure

2CHM is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Allerton CM, Barber CG, Beaumont KC, Brown DG, Cole SM, Ellis D, Lane CA, Maw GN, Mount NM, Rawson DJ, Robinson CM, Street SD, Summerhill NW. A novel series of potent and selective PDE5 inhibitors with potential for high and dose-independent oral bioavailability. J Med Chem. 2006 Jun 15;49(12):3581-94. PMID:16759100 doi:10.1021/jm060113e

Page seeded by OCA on Mon Feb 16 10:00:02 2009

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