3bff: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older editNewer edit →
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,613 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,613 edits
No edit summary
Line 1: Line 1:
[[Image:3bff.jpg|left|200px]]
{{Seed}}
[[Image:3bff.png|left|200px]]


<!--
<!--
Line 9: Line 10:
{{STRUCTURE_3bff|  PDB=3bff  |  SCENE=  }}  
{{STRUCTURE_3bff|  PDB=3bff  |  SCENE=  }}  


'''class A beta-lactamase SED-G238C complexed with faropenem'''
===class A beta-lactamase SED-G238C complexed with faropenem===


==Overview==
SED-1, a class A beta-lactamase from Citrobacter sedlakii, is a CTX-M-type extended-spectrum beta-lactamase that has the ability to hydrolyze expanded-spectrum cephalosporins such as cefotaxime. SED-1 and a SED mutant in which Gly238 has been replaced by a cysteine, forming a disulfide bridge with the other Cys residue located at position 69 (SED-G238C), have been crystallized. The crystals belong to the monoclinic space group C2, with unit-cell parameters a = 188.09, b = 73.65, c = 105.41 A, beta = 121.67 degrees for SED-1 and a = 187.64, b = 73.2, c = 103.89 A, beta = 121.89 degrees for the SED-G238C mutant. X-ray diffraction data were collected to maximum resolutions of 2.4 A for SED-1 and 2.0 A for SED-G238C.


==About this Structure==
==About this Structure==
3BFF is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Citrobacter_sedlakii Citrobacter sedlakii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BFF OCA].  
3BFF is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Citrobacter_sedlakii Citrobacter sedlakii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BFF OCA].  


==Reference==
==Reference==
Crystallization and preliminary X-ray diffraction study of the class A beta-lactamase SED-1 and its mutant SED-G238C from Citrobacter sedlakii., Petrella S, Pernot L, Sougakoff W, Acta Crystallogr D Biol Crystallogr. 2004 Jan;60(Pt 1):125-8. Epub 2003, Dec 18. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14684905 14684905]
<ref group="xtra">PMID:14684905</ref><references group="xtra"/>
[[Category: Beta-lactamase]]
[[Category: Beta-lactamase]]
[[Category: Citrobacter sedlakii]]
[[Category: Citrobacter sedlakii]]
[[Category: Single protein]]
[[Category: Pernot, L.]]
[[Category: Pernot, L.]]
[[Category: Petrella, S.]]
[[Category: Petrella, S.]]
Line 31: Line 28:
[[Category: Faropenem]]
[[Category: Faropenem]]
[[Category: Hydrolase]]
[[Category: Hydrolase]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May  4 20:43:00 2008''
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 11:31:43 2009''

Revision as of 09:31, 16 February 2009

File:3bff.png

Template:STRUCTURE 3bff

class A beta-lactamase SED-G238C complexed with faropenem

About this Structure

3BFF is a 4 chains structure of sequences from Citrobacter sedlakii. Full crystallographic information is available from OCA.

Reference

  1. Petrella S, Pernot L, Sougakoff W. Crystallization and preliminary X-ray diffraction study of the class A beta-lactamase SED-1 and its mutant SED-G238C from Citrobacter sedlakii. Acta Crystallogr D Biol Crystallogr. 2004 Jan;60(Pt 1):125-8. Epub 2003, Dec 18. PMID:14684905

Page seeded by OCA on Mon Feb 16 11:31:43 2009

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "https://proteopedia.org/index.php?title=3bff&oldid=828746"