2nnx: Difference between revisions
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==About this Structure== | ==About this Structure== | ||
2NNX is a | 2NNX is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NNX OCA]. | ||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID:17092942</ref><references group="xtra"/> | |||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Superoxide dismutase]] | [[Category: Superoxide dismutase]] | ||
[[Category: Hart, P J.]] | [[Category: Hart, P J.]] | ||
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[[Category: Superoxide acceptor]] | [[Category: Superoxide acceptor]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 13:11:06 2009'' | ||
Revision as of 11:11, 16 February 2009
Crystal Structure of the H46R, H48Q double mutant of human [Cu-Zn] Superoxide Dismutase
Template:ABSTRACT PUBMED 17092942
Disease
Known disease associated with this structure: Amyotrophic lateral sclerosis, due to SOD1 deficiency OMIM:[147450]
About this Structure
2NNX is a 4 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Wang J, Caruano-Yzermans A, Rodriguez A, Scheurmann JP, Slunt HH, Cao X, Gitlin J, Hart PJ, Borchelt DR. Disease-associated mutations at copper ligand histidine residues of superoxide dismutase 1 diminish the binding of copper and compromise dimer stability. J Biol Chem. 2007 Jan 5;282(1):345-52. Epub 2006 Nov 8. PMID:17092942 doi:10.1074/jbc.M604503200
Page seeded by OCA on Mon Feb 16 13:11:06 2009
