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==About this Structure==
==About this Structure==
2VKU is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VKU OCA].  
2VKU is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VKU OCA].  


==Reference==
==Reference==
X-ray Structure of 4,4'-Dihydroxybenzophenone Mimicking Sterol Substrate in the Active Site of Sterol 14{alpha}-Demethylase (CYP51)., Eddine AN, von Kries JP, Podust MV, Warrier T, Kaufmann SH, Podust LM, J Biol Chem. 2008 May 30;283(22):15152-9. Epub 2008 Mar 26. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18367444 18367444]
<ref group="xtra">PMID:18367444</ref><references group="xtra"/>
[[Category: Mycobacterium tuberculosis]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Single protein]]
[[Category: Sterol 14-demethylase]]
[[Category: Sterol 14-demethylase]]
[[Category: Eddine, A N.]]
[[Category: Eddine, A N.]]
Line 46: Line 45:
[[Category: Sterol biosynthesis]]
[[Category: Sterol biosynthesis]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 15:57:36 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 13:31:24 2009''

Revision as of 11:31, 16 February 2009

File:2vku.png

Template:STRUCTURE 2vku

4,4'-DIHYDROXYBENZOPHENONE MIMICS STEROL SUBSTRATE IN THE BINDING SITE OF STEROL 14ALPHA-DEMETHYLASE (CYP51) IN THE X-RAY STRUCTURE OF THE COMPLEX

Template:ABSTRACT PUBMED 18367444

About this Structure

2VKU is a 1 chain structure of sequence from Mycobacterium tuberculosis. Full crystallographic information is available from OCA.

Reference

  1. Eddine AN, von Kries JP, Podust MV, Warrier T, Kaufmann SH, Podust LM. X-ray structure of 4,4'-dihydroxybenzophenone mimicking sterol substrate in the active site of sterol 14alpha-demethylase (CYP51). J Biol Chem. 2008 May 30;283(22):15152-9. Epub 2008 Mar 26. PMID:18367444 doi:10.1074/jbc.M801145200

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