1o4x: Difference between revisions

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==About this Structure==
==About this Structure==
1O4X is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1O4X OCA].  
1O4X is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1O4X OCA].  


==Reference==
==Reference==
Molecular basis for synergistic transcriptional activation by Oct1 and Sox2 revealed from the solution structure of the 42-kDa Oct1.Sox2.Hoxb1-DNA ternary transcription factor complex., Williams DC Jr, Cai M, Clore GM, J Biol Chem. 2004 Jan 9;279(2):1449-57. Epub 2003 Oct 14. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14559893 14559893]
<ref group="xtra">PMID:14559893</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Protein complex]]
[[Category: Clore, G M.]]
[[Category: Clore, G M.]]
[[Category: Williams, D C.]]
[[Category: Williams, D C.]]
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[[Category: Transcription factor]]
[[Category: Transcription factor]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 17:56:27 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 15:07:11 2009''

Revision as of 13:07, 16 February 2009

File:1o4x.png

Template:STRUCTURE 1o4x

TERNARY COMPLEX OF THE DNA BINDING DOMAINS OF THE OCT1 AND SOX2 TRANSCRIPTION FACTORS WITH A 19MER OLIGONUCLEOTIDE FROM THE HOXB1 REGULATORY ELEMENT

Template:ABSTRACT PUBMED 14559893

Disease

Known disease associated with this structure: Microphthalmia, syndromic 3 OMIM:[184429], Optic nerve hypoplasia and abnormalities of the central nervous system OMIM:[184429]

About this Structure

1O4X is a 4 chains structure of sequences from Homo sapiens. Full experimental information is available from OCA.

Reference

  1. Williams DC Jr, Cai M, Clore GM. Molecular basis for synergistic transcriptional activation by Oct1 and Sox2 revealed from the solution structure of the 42-kDa Oct1.Sox2.Hoxb1-DNA ternary transcription factor complex. J Biol Chem. 2004 Jan 9;279(2):1449-57. Epub 2003 Oct 14. PMID:14559893 doi:https://dx.doi.org/10.1074/jbc.M309790200

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