2hh4: Difference between revisions

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==About this Structure==
==About this Structure==
2HH4 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HH4 OCA].  
2HH4 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HH4 OCA].  


==Reference==
==Reference==
Toward the active conformation of insulin: stereospecific modulation of a structural switch in the B chain., Hua QX, Nakagawa S, Hu SQ, Jia W, Wang S, Weiss MA, J Biol Chem. 2006 Aug 25;281(34):24900-9. Epub 2006 Jun 8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16762918 16762918]
<ref group="xtra">PMID:16762918</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Protein complex]]
[[Category: Hu, S Q.]]
[[Category: Hu, S Q.]]
[[Category: Hua, Q X.]]
[[Category: Hua, Q X.]]
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[[Category: Mutant]]
[[Category: Mutant]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 17:58:50 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 15:09:06 2009''

Revision as of 13:09, 16 February 2009

File:2hh4.png

Template:STRUCTURE 2hh4

NMR structure of human insulin mutant GLY-B8-D-SER, HIS-B10-ASP PRO-B28-LYS, LYS-B29-PRO, 20 structures

Template:ABSTRACT PUBMED 16762918

Disease

Known disease associated with this structure: Diabetes mellitus, rare form OMIM:[176730], Hyperproinsulinemia, familial OMIM:[176730], MODY, one form OMIM:[176730]

About this Structure

2HH4 is a 2 chains structure of sequences from Homo sapiens. Full experimental information is available from OCA.

Reference

  1. Hua QX, Nakagawa S, Hu SQ, Jia W, Wang S, Weiss MA. Toward the active conformation of insulin: stereospecific modulation of a structural switch in the B chain. J Biol Chem. 2006 Aug 25;281(34):24900-9. Epub 2006 Jun 8. PMID:16762918 doi:https://dx.doi.org/10.1074/jbc.M602691200

Page seeded by OCA on Mon Feb 16 15:09:06 2009

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