6pax: Difference between revisions
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==Disease== | ==Disease== | ||
Known disease associated with this structure: Aniridia | Known disease associated with this structure: Aniridia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=607108 607108]], Cataract with late-onset corneal dystrophy OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=607108 607108]], Coloboma of optic nerve OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=607108 607108]], Coloboma, ocular OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=607108 607108]], Ectopia pupillae OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=607108 607108]], Foveal hyperplasia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=607108 607108]], Gillespie synd OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=607108 607108]], Keratitis OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=607108 607108]], Morning glory disc anomaly OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=607108 607108]], Optic nerve hypoplasia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=607108 607108]], Peters anomaly OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=607108 607108]] | ||
==About this Structure== | ==About this Structure== | ||
6PAX is a | 6PAX is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PAX OCA]. | ||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID:10346815</ref><references group="xtra"/> | |||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Epstein, J A.]] | [[Category: Epstein, J A.]] | ||
[[Category: Maas, R L.]] | [[Category: Maas, R L.]] | ||
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[[Category: Transcription]] | [[Category: Transcription]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 17:56:01 2009'' | ||
Revision as of 15:56, 16 February 2009
CRYSTAL STRUCTURE OF THE HUMAN PAX-6 PAIRED DOMAIN-DNA COMPLEX REVEALS A GENERAL MODEL FOR PAX PROTEIN-DNA INTERACTIONS
Template:ABSTRACT PUBMED 10346815
Disease
Known disease associated with this structure: Aniridia OMIM:[607108], Cataract with late-onset corneal dystrophy OMIM:[607108], Coloboma of optic nerve OMIM:[607108], Coloboma, ocular OMIM:[607108], Ectopia pupillae OMIM:[607108], Foveal hyperplasia OMIM:[607108], Gillespie synd OMIM:[607108], Keratitis OMIM:[607108], Morning glory disc anomaly OMIM:[607108], Optic nerve hypoplasia OMIM:[607108], Peters anomaly OMIM:[607108]
About this Structure
6PAX is a 3 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Xu HE, Rould MA, Xu W, Epstein JA, Maas RL, Pabo CO. Crystal structure of the human Pax6 paired domain-DNA complex reveals specific roles for the linker region and carboxy-terminal subdomain in DNA binding. Genes Dev. 1999 May 15;13(10):1263-75. PMID:10346815
Page seeded by OCA on Mon Feb 16 17:56:01 2009
