1pd9: Difference between revisions

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==About this Structure==
==About this Structure==
1PD9 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PD9 OCA].  
1PD9 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PD9 OCA].  


==Reference==
==Reference==
Analysis of three crystal structure determinations of a 5-methyl-6-N-methylanilino pyridopyrimidine antifolate complex with human dihydrofolate reductase., Cody V, Luft JR, Pangborn W, Gangjee A, Acta Crystallogr D Biol Crystallogr. 2003 Sep;59(Pt 9):1603-9. Epub 2003, Aug 19. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12925791 12925791]
<ref group="xtra">PMID:12925791</ref><references group="xtra"/>
[[Category: Dihydrofolate reductase]]
[[Category: Dihydrofolate reductase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Cody, V.]]
[[Category: Cody, V.]]
[[Category: Gangjee, A.]]
[[Category: Gangjee, A.]]
Line 36: Line 35:
[[Category: Human dihydrofolate reductase inhibitor complex]]
[[Category: Human dihydrofolate reductase inhibitor complex]]


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Revision as of 16:07, 16 February 2009

File:1pd9.png

Template:STRUCTURE 1pd9

Analysis of Three Crystal Structure Determinations of a 5-Methyl-6-N-Methylanilino Pyridopyrimidine antifolate Complex with Human Dihydrofolate Reductase

Template:ABSTRACT PUBMED 12925791

Disease

Known disease associated with this structure: Anemia, megaloblastic, due to DHFR deficiency (1) OMIM:[126060]

About this Structure

1PD9 is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Cody V, Luft JR, Pangborn W, Gangjee A. Analysis of three crystal structure determinations of a 5-methyl-6-N-methylanilino pyridopyrimidine antifolate complex with human dihydrofolate reductase. Acta Crystallogr D Biol Crystallogr. 2003 Sep;59(Pt 9):1603-9. Epub 2003, Aug 19. PMID:12925791

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