1q2p: Difference between revisions

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==About this Structure==
==About this Structure==
1Q2P is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Klebsiella_pneumoniae Klebsiella pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Q2P OCA].  
1Q2P is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Klebsiella_pneumoniae Klebsiella pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Q2P OCA].  


==Reference==
==Reference==
Structure-activity relationship of 6-methylidene penems bearing tricyclic heterocycles as broad-spectrum beta-lactamase inhibitors: crystallographic structures show unexpected binding of 1,4-thiazepine intermediates., Venkatesan AM, Gu Y, Dos Santos O, Abe T, Agarwal A, Yang Y, Petersen PJ, Weiss WJ, Mansour TS, Nukaga M, Hujer AM, Bonomo RA, Knox JR, J Med Chem. 2004 Dec 16;47(26):6556-68. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15588091 15588091]
<ref group="xtra">PMID:15588091</ref><references group="xtra"/>
[[Category: Beta-lactamase]]
[[Category: Beta-lactamase]]
[[Category: Klebsiella pneumoniae]]
[[Category: Klebsiella pneumoniae]]
[[Category: Single protein]]
[[Category: Bonomo, R A.]]
[[Category: Bonomo, R A.]]
[[Category: Hujer, A.]]
[[Category: Hujer, A.]]
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[[Category: Inhibition]]
[[Category: Inhibition]]


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Revision as of 16:35, 16 February 2009

File:1q2p.png

Template:STRUCTURE 1q2p

SHV-1 class A beta-lactamase complexed with penem WAY185229

Template:ABSTRACT PUBMED 15588091

About this Structure

1Q2P is a 1 chain structure of sequence from Klebsiella pneumoniae. Full crystallographic information is available from OCA.

Reference

  1. Venkatesan AM, Gu Y, Dos Santos O, Abe T, Agarwal A, Yang Y, Petersen PJ, Weiss WJ, Mansour TS, Nukaga M, Hujer AM, Bonomo RA, Knox JR. Structure-activity relationship of 6-methylidene penems bearing tricyclic heterocycles as broad-spectrum beta-lactamase inhibitors: crystallographic structures show unexpected binding of 1,4-thiazepine intermediates. J Med Chem. 2004 Dec 16;47(26):6556-68. PMID:15588091 doi:10.1021/jm049680x

Page seeded by OCA on Mon Feb 16 18:35:40 2009

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