3b2w: Difference between revisions
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==About this Structure== | ==About this Structure== | ||
3B2W is a | 3B2W is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3B2W OCA]. | ||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID:18083554</ref><references group="xtra"/> | |||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Non-specific protein-tyrosine kinase]] | [[Category: Non-specific protein-tyrosine kinase]] | ||
[[Category: Huang, X.]] | [[Category: Huang, X.]] | ||
[[Category: Alternative splicing]] | [[Category: Alternative splicing]] | ||
| Line 51: | Line 50: | ||
[[Category: Tyrosine-protein kinase]] | [[Category: Tyrosine-protein kinase]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 18:35:55 2009'' | ||
Revision as of 16:35, 16 February 2009
Crystal structure of pyrimidine amide 11 bound to Lck
Template:ABSTRACT PUBMED 18083554
Disease
Known disease associated with this structure: SCID due to LCK deficiency OMIM:[153390]
About this Structure
3B2W is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Deak HL, Newcomb JR, Nunes JJ, Boucher C, Cheng AC, DiMauro EF, Epstein LF, Gallant P, Hodous BL, Huang X, Lee JH, Patel VF, Schneider S, Turci SM, Zhu X. N-(3-(phenylcarbamoyl)arylpyrimidine)-5-carboxamides as potent and selective inhibitors of Lck: structure, synthesis and SAR. Bioorg Med Chem Lett. 2008 Feb 1;18(3):1172-6. Epub 2007 Dec 5. PMID:18083554 doi:https://dx.doi.org/10.1016/j.bmcl.2007.11.123
Page seeded by OCA on Mon Feb 16 18:35:55 2009
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Homo sapiens
- Non-specific protein-tyrosine kinase
- Huang, X.
- Alternative splicing
- Atp-binding
- Chromosomal rearrangement
- Cytoplasm
- Disease mutation
- Host-virus interaction
- Kinase domain
- Lck
- Lipoprotein
- Membrane
- Myristate
- Nucleotide-binding
- Palmitate
- Phosphorylation
- Proto-oncogene
- Sh2 domain
- Sh3 domain
- Transferase
- Tyrosine-protein kinase
