2r3t: Difference between revisions

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==About this Structure==
==About this Structure==
2R3T is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R3T OCA].  
2R3T is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R3T OCA].  


==Reference==
==Reference==
Structural and Kinetic Analysis of Pyrrolidine-Based Inhibitors of the Drug-Resistant Ile84Val Mutant of HIV-1 Protease., Bottcher J, Blum A, Heine A, Diederich WE, Klebe G, J Mol Biol. 2008 Jul 29. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18692068 18692068]
<ref group="xtra">PMID:18692068</ref><references group="xtra"/>
[[Category: HIV-1 retropepsin]]
[[Category: HIV-1 retropepsin]]
[[Category: Human immunodeficiency virus 1]]
[[Category: Human immunodeficiency virus 1]]
[[Category: Single protein]]
[[Category: Blum, A.]]
[[Category: Pdbx_ordinal=, <PDBx:audit_author.]]
[[Category: Boettcher, J.]]
[[Category: Diederich, W E.]]
[[Category: Heine, A.]]
[[Category: Klebe, G.]]
[[Category: Aspartyl protease]]
[[Category: Aspartyl protease]]
[[Category: Hydrolase]]
[[Category: Hydrolase]]
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[[Category: Protein-ligand complex]]
[[Category: Protein-ligand complex]]


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Revision as of 17:59, 16 February 2009

File:2r3t.png

Template:STRUCTURE 2r3t

I50V HIV-1 protease mutant in complex with a carbamoyl decorated pyrrolidine-based inhibitor

Template:ABSTRACT PUBMED 18692068

About this Structure

2R3T is a 2 chains structure of sequences from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.

Reference

  1. Bottcher J, Blum A, Heine A, Diederich WE, Klebe G. Structural and kinetic analysis of pyrrolidine-based inhibitors of the drug-resistant Ile84Val mutant of HIV-1 protease. J Mol Biol. 2008 Nov 7;383(2):347-57. Epub 2008 Jul 29. PMID:18692068 doi:10.1016/j.jmb.2008.07.062

Page seeded by OCA on Mon Feb 16 19:59:25 2009

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