2i40: Difference between revisions

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==About this Structure==
==About this Structure==
2I40 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I40 OCA].  
2I40 is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I40 OCA].  


==Reference==
==Reference==
5-(1H-Benzimidazol-1-yl)-3-alkoxy-2-thiophenecarbonitriles as potent, selective, inhibitors of IKK-epsilon kinase., Bamborough P, Christopher JA, Cutler GJ, Dickson MC, Mellor GW, Morey JV, Patel CB, Shewchuk LM, Bioorg Med Chem Lett. 2006 Dec 15;16(24):6236-40. Epub 2006 Sep 25. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16997559 16997559]
<ref group="xtra">PMID:16997559</ref><references group="xtra"/>
[[Category: Cyclin-dependent kinase]]
[[Category: Cyclin-dependent kinase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Protein complex]]
[[Category: Shewchuk, L M.]]
[[Category: Shewchuk, L M.]]
[[Category: Cdk2]]
[[Category: Cdk2]]
Line 32: Line 31:
[[Category: Kinase]]
[[Category: Kinase]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 00:51:55 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 20:41:37 2009''

Revision as of 18:41, 16 February 2009

File:2i40.png

Template:STRUCTURE 2i40

Cdk2/Cyclin A complexed with a thiophene carboxamide inhibitor

Template:ABSTRACT PUBMED 16997559

About this Structure

2I40 is a 4 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Bamborough P, Christopher JA, Cutler GJ, Dickson MC, Mellor GW, Morey JV, Patel CB, Shewchuk LM. 5-(1H-Benzimidazol-1-yl)-3-alkoxy-2-thiophenecarbonitriles as potent, selective, inhibitors of IKK-epsilon kinase. Bioorg Med Chem Lett. 2006 Dec 15;16(24):6236-40. Epub 2006 Sep 25. PMID:16997559 doi:10.1016/j.bmcl.2006.09.018

Page seeded by OCA on Mon Feb 16 20:41:37 2009

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