2hs2: Difference between revisions

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==About this Structure==
==About this Structure==
2HS2 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HS2 OCA].  
2HS2 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HS2 OCA].  


==Reference==
==Reference==
Ultra-high resolution crystal structure of HIV-1 protease mutant reveals two binding sites for clinical inhibitor TMC114., Kovalevsky AY, Liu F, Leshchenko S, Ghosh AK, Louis JM, Harrison RW, Weber IT, J Mol Biol. 2006 Oct 13;363(1):161-73. Epub 2006 Aug 4. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16962136 16962136]
<ref group="xtra">PMID:16962136</ref><references group="xtra"/>
[[Category: Human immunodeficiency virus 1]]
[[Category: Human immunodeficiency virus 1]]
[[Category: Single protein]]
[[Category: Kovalevsky, A Y.]]
[[Category: Kovalevsky, A Y.]]
[[Category: Liu, F.]]
[[Category: Liu, F.]]
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[[Category: Aspartic protease active site surface binding site]]
[[Category: Aspartic protease active site surface binding site]]


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Revision as of 19:15, 16 February 2009

File:2hs2.png

Template:STRUCTURE 2hs2

Crystal structure of M46L mutant of HIV-1 protease complexed with TMC114 (darunavir)

Template:ABSTRACT PUBMED 16962136

About this Structure

2HS2 is a 2 chains structure of sequences from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.

Reference

  1. Kovalevsky AY, Liu F, Leshchenko S, Ghosh AK, Louis JM, Harrison RW, Weber IT. Ultra-high resolution crystal structure of HIV-1 protease mutant reveals two binding sites for clinical inhibitor TMC114. J Mol Biol. 2006 Oct 13;363(1):161-73. Epub 2006 Aug 4. PMID:16962136 doi:10.1016/j.jmb.2006.08.007

Page seeded by OCA on Mon Feb 16 21:15:50 2009

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