1py2: Difference between revisions

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==About this Structure==
==About this Structure==
1PY2 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PY2 OCA].  
1PY2 is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PY2 OCA].  


==Reference==
==Reference==
Potent small-molecule binding to a dynamic hot spot on IL-2., Thanos CD, Randal M, Wells JA, J Am Chem Soc. 2003 Dec 17;125(50):15280-1. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14664558 14664558]
<ref group="xtra">PMID:14664558</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Randal, M.]]
[[Category: Randal, M.]]
[[Category: Thanos, C D.]]
[[Category: Thanos, C D.]]
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[[Category: Small molecule]]
[[Category: Small molecule]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 04:15:37 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 23:54:58 2009''

Revision as of 21:55, 16 February 2009

File:1py2.png

Template:STRUCTURE 1py2

Structure of a 60 nM Small Molecule Bound to a Hot Spot on IL-2

Template:ABSTRACT PUBMED 14664558

Disease

Known disease associated with this structure: Severe combined immunodeficiency due to IL2 deficiency OMIM:[147680]

About this Structure

1PY2 is a 4 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Thanos CD, Randal M, Wells JA. Potent small-molecule binding to a dynamic hot spot on IL-2. J Am Chem Soc. 2003 Dec 17;125(50):15280-1. PMID:14664558 doi:10.1021/ja0382617

Page seeded by OCA on Mon Feb 16 23:54:58 2009

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