2guo: Difference between revisions

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==About this Structure==
==About this Structure==
2GUO is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GUO OCA].  
2GUO is a 6 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GUO OCA].  


==Reference==
==Reference==
Structures of MART-126/27-35 Peptide/HLA-A2 complexes reveal a remarkable disconnect between antigen structural homology and T cell recognition., Borbulevych OY, Insaidoo FK, Baxter TK, Powell DJ Jr, Johnson LA, Restifo NP, Baker BM, J Mol Biol. 2007 Oct 5;372(5):1123-36. Epub 2007 Jul 26. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17719062 17719062]
<ref group="xtra">PMID:17719062</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Protein complex]]
[[Category: Baker, B M.]]
[[Category: Baker, B M.]]
[[Category: Borbulevych, O Y.]]
[[Category: Borbulevych, O Y.]]
Line 39: Line 38:
[[Category: X-ray crystallography]]
[[Category: X-ray crystallography]]


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Revision as of 02:00, 17 February 2009

File:2guo.png

Template:STRUCTURE 2guo

Human Class I MHC HLA-A2 in complex with the native nonameric Melan-A/MART-1(27-35) peptide

Template:ABSTRACT PUBMED 17719062

Disease

Known disease associated with this structure: Abacavir hypersensitivity, susceptibility to OMIM:[142800], Ankylosing spondylitis, susceptibility to, 1 OMIM:[142800], Stevens-Johnson syndrome, susceptibility to OMIM:[142800], Hypoproteinemia, hypercatabolic OMIM:[109700]

About this Structure

2GUO is a 6 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Borbulevych OY, Insaidoo FK, Baxter TK, Powell DJ Jr, Johnson LA, Restifo NP, Baker BM. Structures of MART-126/27-35 Peptide/HLA-A2 complexes reveal a remarkable disconnect between antigen structural homology and T cell recognition. J Mol Biol. 2007 Oct 5;372(5):1123-36. Epub 2007 Jul 26. PMID:17719062 doi:10.1016/j.jmb.2007.07.025

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