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| ==About this Structure== | | ==About this Structure== |
| 3B7R is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3B7R OCA]. | | 3B7R is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3B7R OCA]. |
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| ==Reference== | | ==Reference== |
| Structure-based dissection of the active site chemistry of leukotriene a4 hydrolase: implications for m1 aminopeptidases and inhibitor design., Tholander F, Muroya A, Roques BP, Fournie-Zaluski MC, Thunnissen MM, Haeggstrom JZ, Chem Biol. 2008 Sep 22;15(9):920-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18804029 18804029]
| | <ref group="xtra">PMID:18804029</ref><ref group="xtra">PMID:17357161</ref><ref group="xtra">PMID:15078870</ref><ref group="xtra">PMID:11675384</ref><ref group="xtra">PMID:11917124</ref><ref group="xtra">PMID:11175901</ref><references group="xtra"/> |
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| Assay for rapid analysis of the tri-peptidase activity of LTA4 hydrolase., Tholander F, Haeggstrom JZ, Proteins. 2007 Jun 1;67(4):1113-8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17357161 17357161]
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| Leukotriene A4 hydrolase: identification of a common carboxylate recognition site for the epoxide hydrolase and aminopeptidase substrates., Rudberg PC, Tholander F, Andberg M, Thunnissen MM, Haeggstrom JZ, J Biol Chem. 2004 Jun 25;279(26):27376-82. Epub 2004 Apr 12. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15078870 15078870]
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| Leukotriene A4 hydrolase/aminopeptidase. Glutamate 271 is a catalytic residue with specific roles in two distinct enzyme mechanisms., Rudberg PC, Tholander F, Thunnissen MM, Haeggstrom JZ, J Biol Chem. 2002 Jan 11;277(2):1398-404. Epub 2001 Oct 23. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11675384 11675384]
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| Leukotriene A4 hydrolase: selective abrogation of leukotriene B4 formation by mutation of aspartic acid 375., Rudberg PC, Tholander F, Thunnissen MM, Samuelsson B, Haeggstrom JZ, Proc Natl Acad Sci U S A. 2002 Apr 2;99(7):4215-20. Epub 2002 Mar 26. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11917124 11917124]
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| Crystal structure of human leukotriene A(4) hydrolase, a bifunctional enzyme in inflammation., Thunnissen MM, Nordlund P, Haeggstrom JZ, Nat Struct Biol. 2001 Feb;8(2):131-5. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11175901 11175901]
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| [[Category: Homo sapiens]] | | [[Category: Homo sapiens]] |
| [[Category: Single protein]]
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| [[Category: Fournie-Zaluski, M C.]] | | [[Category: Fournie-Zaluski, M C.]] |
| [[Category: Haeggstrom, J.]] | | [[Category: Haeggstrom, J.]] |
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| [[Category: Zinc]] | | [[Category: Zinc]] |
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| ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 8 09:05:33 2008'' | | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 04:43:22 2009'' |
