1pl0: Difference between revisions
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==About this Structure== | ==About this Structure== | ||
1PL0 is a | 1PL0 is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PL0 OCA]. | ||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID:14966129</ref><references group="xtra"/> | |||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Beardsley, G P.]] | [[Category: Beardsley, G P.]] | ||
[[Category: Cheong, C G.]] | [[Category: Cheong, C G.]] | ||
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[[Category: Xanthosine monophosphate]] | [[Category: Xanthosine monophosphate]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 08:19:06 2009'' | ||
Revision as of 06:19, 17 February 2009
Crystal structure of human ATIC in complex with folate-based inhibitor, BW2315U89UC
Template:ABSTRACT PUBMED 14966129
Disease
Known disease associated with this structure: AICA-ribosiduria due to ATIC deficiency OMIM:[601731]
About this Structure
1PL0 is a 4 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Cheong CG, Wolan DW, Greasley SE, Horton PA, Beardsley GP, Wilson IA. Crystal structures of human bifunctional enzyme aminoimidazole-4-carboxamide ribonucleotide transformylase/IMP cyclohydrolase in complex with potent sulfonyl-containing antifolates. J Biol Chem. 2004 Apr 23;279(17):18034-45. Epub 2004 Feb 13. PMID:14966129 doi:10.1074/jbc.M313691200
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