2iit: Difference between revisions
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==About this Structure== | ==About this Structure== | ||
2IIT is a | 2IIT is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IIT OCA]. | ||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID:17055272</ref><references group="xtra"/> | |||
[[Category: Dipeptidyl-peptidase IV]] | [[Category: Dipeptidyl-peptidase IV]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Biftu, T.]] | [[Category: Biftu, T.]] | ||
[[Category: Scapin, G.]] | [[Category: Scapin, G.]] | ||
| Line 35: | Line 34: | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 08:24:32 2009'' | ||
Revision as of 06:24, 17 February 2009
Human dipeptidyl peptidase 4 in complex with a diazepan-2-one inhibitor
Template:ABSTRACT PUBMED 17055272
About this Structure
2IIT is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Biftu T, Feng D, Qian X, Liang GB, Kieczykowski G, Eiermann G, He H, Leiting B, Lyons K, Petrov A, Sinha-Roy R, Zhang B, Scapin G, Patel S, Gao YD, Singh S, Wu J, Zhang X, Thornberry NA, Weber AE. (3R)-4-[(3R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoyl]-3-(2,2,2-trifluoro ethyl)-1,4-diazepan-2-one, a selective dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes. Bioorg Med Chem Lett. 2007 Jan 1;17(1):49-52. Epub 2006 Oct 5. PMID:17055272 doi:10.1016/j.bmcl.2006.09.099
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