2o0t: Difference between revisions

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[[Image:2o0t.~~gif~~|left|200px]]

[[Image:2o0t.png|left|200px]]

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~~'''~~The three dimensional structure of diaminopimelate decarboxylase from Mycobacterium tuberculosis reveals a tetrameric enzyme organisation~~'''~~

===The three dimensional structure of diaminopimelate decarboxylase from Mycobacterium tuberculosis reveals a tetrameric enzyme organisation===

~~==Overview==~~

Diaminopimelate decarboxylase from Mycobacterium tuberculosis (LysA, DAPDC, Rv1293) has been cloned and heterologously expressed in Escherichia coli, purified using standard chromatographic techniques and crystallized. Preliminary diffraction data analysis suggests the presence of a homotetramer in the asymmetric unit.

==About this Structure==

2O0T is a ~~[[Single protein]]~~ structure of ~~sequence~~ from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O0T OCA].

2O0T is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O0T OCA].

==Reference==

Cloning, expression, purification, crystallization and preliminary X-ray diffraction analysis of LysA (Rv1293) from Mycobacterium tuberculosis., Kefala G, Perry LJ, Weiss MS, Acta Crystallogr Sect F Struct Biol Cryst Commun. 2005 Aug 1;61(Pt, 8):782-4. Epub 2005 Jul 30. PMID:~~[http:~~//~~www.ncbi.nlm.nih.gov/pubmed/16511157 16511157]~~

[[Category: Diaminopimelate decarboxylase]]

[[Category: Mycobacterium tuberculosis]]

~~[[Category: Single protein]]~~

[[Category: Kefala, G.]]

[[Category: TBSGC, TB Structural Genomics Consortium.]]

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[[Category: Tb structural genomics consortium]]

[[Category: Tbsgc]]

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Sun May 4 10~~:09:~~53 2008~~''

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 09:57:17 2009''

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-[[Image:2o0t.gif|left|200px]]
+{{Seed}}
+[[Image:2o0t.png|left|200px]]
 <!--
@@ Line 9: / Line 10: @@
 {{STRUCTURE_2o0t|  PDB=2o0t  |  SCENE=  }}
-'''The three dimensional structure of diaminopimelate decarboxylase from Mycobacterium tuberculosis reveals a tetrameric enzyme organisation'''
+===The three dimensional structure of diaminopimelate decarboxylase from Mycobacterium tuberculosis reveals a tetrameric enzyme organisation===
-==Overview==
-Diaminopimelate decarboxylase from Mycobacterium tuberculosis (LysA, DAPDC, Rv1293) has been cloned and heterologously expressed in Escherichia coli, purified using standard chromatographic techniques and crystallized. Preliminary diffraction data analysis suggests the presence of a homotetramer in the asymmetric unit.
 ==About this Structure==
-O0T is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O0T OCA].
+O0T is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O0T OCA].
 ==Reference==
-Cloning, expression, purification, crystallization and preliminary X-ray diffraction analysis of LysA (Rv1293) from Mycobacterium tuberculosis., Kefala G, Perry LJ, Weiss MS, Acta Crystallogr Sect F Struct Biol Cryst Commun. 2005 Aug 1;61(Pt, 8):782-4. Epub 2005 Jul 30. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16511157 16511157]
+<ref group="xtra">PMID:16511157</ref><references group="xtra"/>
 [[Category: Diaminopimelate decarboxylase]]
 [[Category: Mycobacterium tuberculosis]]
-[[Category: Single protein]]
 [[Category: Kefala, G.]]
 [[Category: TBSGC, TB Structural Genomics Consortium.]]
@@ Line 33: / Line 30: @@
 [[Category: Tb structural genomics consortium]]
 [[Category: Tbsgc]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May  4 10:09:53 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 09:57:17 2009''