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==About this Structure==
==About this Structure==
2ITZ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ITZ OCA].  
2ITZ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ITZ OCA].  


==Reference==
==Reference==
Structures of lung cancer-derived EGFR mutants and inhibitor complexes: mechanism of activation and insights into differential inhibitor sensitivity., Yun CH, Boggon TJ, Li Y, Woo MS, Greulich H, Meyerson M, Eck MJ, Cancer Cell. 2007 Mar;11(3):217-27. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17349580 17349580]
<ref group="xtra">PMID:17349580</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Receptor protein-tyrosine kinase]]
[[Category: Receptor protein-tyrosine kinase]]
[[Category: Single protein]]
[[Category: Boggon, T J.]]
[[Category: Boggon, T J.]]
[[Category: Eck, M J.]]
[[Category: Eck, M J.]]
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[[Category: Zd1839]]
[[Category: Zd1839]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 15:24:52 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 11:20:35 2009''

Revision as of 09:20, 17 February 2009

File:2itz.png

Template:STRUCTURE 2itz

CRYSTAL STRUCTURE OF EGFR KINASE DOMAIN L858R MUTATION IN COMPLEX WITH IRESSA

Template:ABSTRACT PUBMED 17349580

About this Structure

2ITZ is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Yun CH, Boggon TJ, Li Y, Woo MS, Greulich H, Meyerson M, Eck MJ. Structures of lung cancer-derived EGFR mutants and inhibitor complexes: mechanism of activation and insights into differential inhibitor sensitivity. Cancer Cell. 2007 Mar;11(3):217-27. PMID:17349580 doi:https://dx.doi.org/10.1016/j.ccr.2006.12.017

Page seeded by OCA on Tue Feb 17 11:20:35 2009

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